3 Stocks That Have More Than Doubled the S&P 500’s Return This Year

Quick Read

  • SanDisk’s 599% gain leads the group, with 8x forward earnings and $93.9B in multi-year contracts suggesting the fundamentals haven’t fully caught up to the stock.

  • Moderna’s melanoma vaccine trial with Merck hit a landmark result, but the stock trades above analyst targets on a company still posting hundreds of millions in losses.

  • Dell’s record $95B AI server backlog extends revenue visibility into next year, but a 47% free cash flow drop and 30x valuation limit further upside.

  • Just released. Our analysts combed the entire stock market and named the ten best stocks to buy right now, and Dell Technologies didn’t make the cut. Enter your email to see the names that beat DELL. The report is free. Enter your email and see if any of your stocks made the cut.

Through Oct. 7, the S&P 500 has returned 13.75% year to date. That is a solid year by historical standards. Three stocks have gone far past it, with gains measured in the hundreds of percent over the same window. The harder question for investors is whether any of these runs still has room, or whether the good news is already in the price.

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To rank them, we used four tests: year-to-date return against the index, earnings quality (profits and earnings beats), forward visibility (backlog, contracts and guidance), and valuation relative to what the business is expected to earn. Counting down from #3, we cover Moderna (NASDAQ:MRNA), Dell Technologies (NYSE:DELL) and SanDisk (NASDAQ:SNDK).

#3 Moderna: A Cancer Vaccine Win Sparked a Biotech Rerating

Moderna has returned nearly 537% this year, rising from $29.49 to $196.48. The catalyst was cancer treatment. Moderna said its Phase 3 intismeran melanoma study with Merck (NYSE:MRK) produced the first statistically significant and clinically meaningful adjuvant benefit of its kind. Detailed data was set for an ESMO presentation, and the stock gained 28.79% over the past month.

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The operating business has not caught up. Second-quarter revenue was $145 million, +2.1% YoY, and the net loss came to $782 million. Management guides to up to 10% revenue growth for 2026. The shares now trade well above the average analyst target of $120.67, and they fell 7.75% in the latest session. The pipeline win is real. The valuation already assumes it turns into commercial revenue.

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